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barasertib

Synonyms

SourcesNames Used
CTRPv2barasertib
PharmacoGx barasertib

External IDs

DatabaseIdentifier
Smiles: CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)ncnc2c1
Pubchem: 11497983

Annotated Targets

AURKA, AURKB

FDA Approval Status

Not Approved
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Top molecular features associated with response to barasertib


Feature TypeStandardized
Nominal ANOVA
mRNA CTRPv2 pan-cancer AAC 0.24 1e-11
mRNA GDSC1000 pan-cancer AAC -0.19 3e-09
mRNA GDSC1000 pan-cancer AAC -0.16 2e-07
mRNA CTRPv2 pan-cancer AAC -0.17 1e-06
mRNA CTRPv2 pan-cancer AAC 0.18 2e-06
mRNA GDSC1000 pan-cancer AAC -0.14 2e-06
mRNA CTRPv2 pan-cancer AAC -0.15 2e-05
mRNA CTRPv2 pan-cancer AAC -0.16 4e-05
mRNA CTRPv2 pan-cancer AAC -0.15 4e-05
mRNA GDSC1000 pan-cancer AAC -0.12 5e-05
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