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AZD-7545

Synonyms

SourcesNames Used
CTRPv2AZD7545
PharmacoGx AZD-7545

External IDs

DatabaseIdentifier
Smiles: CC(C(=O)NC1=C(C=C(C=C1)S(=O)(=O)C2=CC=C(C=C2)C(=O)N(C)C)Cl)(C(F)(F)F)O
Inchikey: DTDZLJHKVNTQGZ-GOSISDBHSA-N
Pubchem: 16741245

Annotated Targets

PDK1, PDK2

FDA Approval Status

Not Approved
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Top molecular features associated with response to AZD-7545


Feature TypeStandardized
Nominal ANOVA
mRNA CTRPv2 pan-cancer AAC 0.46 8e-14
mRNA CTRPv2 pan-cancer AAC 0.37 3e-08
mRNA CTRPv2 pan-cancer AAC 0.37 4e-08
mRNA CTRPv2 pan-cancer AAC 0.36 1e-07
mRNA CTRPv2 pan-cancer AAC 0.31 2e-06
mRNA CTRPv2 pan-cancer AAC 0.17 6e-06
mRNA GDSC1000 pan-cancer AAC 0.23 9e-06
mRNA CTRPv2 pan-cancer AAC -0.15 9e-06
mRNA CCLE pan-cancer AAC 0.2 1e-05
mRNA CTRPv2 pan-cancer AAC 0.3 2e-05
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