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17-AAG

Synonyms

SourcesNames Used
CCLE, GDSC1000, GRAY17-AAG
FIMMTanespimycin
CTRPv2tanespimycin
PharmacoGx 17-AAG

External IDs

DatabaseIdentifier
Smiles: CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC
Inchikey: AYUNIORJHRXIBJ-TXHRRWQRSA-N
Pubchem: 6505803

FDA Approval Status

Not Approved
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Top molecular features associated with response to 17-AAG


Feature TypeStandardized
Nominal ANOVA
mRNA CTRPv2 pan-cancer AAC 0.44 1e-10
mRNA CTRPv2 pan-cancer AAC 0.39 1e-08
mRNA GDSC1000 pan-cancer AAC 0.18 6e-08
mRNA GDSC1000 pan-cancer AAC 0.29 3e-07
mRNA GDSC1000 pan-cancer AAC 0.16 4e-06
mRNA GDSC1000 pan-cancer AAC 0.15 1e-05
mRNA GDSC1000 pan-cancer AAC 0.16 1e-05
mRNA CTRPv2 pan-cancer AAC 0.16 5e-05
mRNA CTRPv2 pan-cancer AAC -0.12 0.0003
mRNA GDSC1000 pan-cancer AAC 0.14 0.0004
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