1. Home/
  2. Compounds/
  3. Vorinostat

Vorinostat

Synonyms

SourcesNames Used
GDSC1000, GRAY, FIMMVorinostat
gCSI, CTRPv2vorinostat
PharmacoGx Vorinostat

External IDs

DatabaseIdentifier
Smiles: C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
Inchikey: WAEXFXRVDQXREF-UHFFFAOYSA-N
Pubchem: 5311

Annotated Targets

HDAC6, HDAC1, HDAC2, HDAC3, HDAC10, HDAC11, HDAC5, HDAC8, HDAC9

Cell lines tested with Vorinostat

1289 cell lines have been tested with this compound, using data from 5 dataset(s).
Hs-578-T breast GDSC1000, gCSI, GRAY, FIMM, CTRPv210
MDA-MB-453 breast GDSC1000, gCSI, GRAY, FIMM, CTRPv28
HCC1954 breast GDSC1000, gCSI, GRAY, CTRPv27
MDA-MB-231 breast GDSC1000, gCSI, GRAY, FIMM, CTRPv27
HCC1419 breast GDSC1000, gCSI, GRAY, CTRPv27
BT-474 breast GDSC1000, gCSI, GRAY, FIMM, CTRPv26
BT-20 breast GDSC1000, gCSI, GRAY, CTRPv26
BT-549 breast GDSC1000, gCSI, GRAY, FIMM, CTRPv26
HCC38 breast GDSC1000, gCSI, GRAY, CTRPv26
MCF7 breast GDSC1000, gCSI, GRAY, FIMM, CTRPv26
Download CSV
Download Data as CSV

Top molecular features associated with response to Vorinostat


Feature TypeStandardized
Nominal ANOVA
mRNA GADD45B GDSC1000 AAC -0.27 1e-17
mRNA SQSTM1 GDSC1000 AAC -0.28 4e-16
mRNA PRSS23 GDSC1000 AAC -0.33 3e-15
mRNA MYOF GDSC1000 AAC -0.33 7e-15
mRNA MEX3A GDSC1000 AAC 0.27 8e-15
mRNA CYR61 GDSC1000 AAC -0.33 3e-14
mRNA ATP6V0E1 GDSC1000 AAC -0.24 9e-14
mRNA RBMX GDSC1000 AAC 0.25 9e-14
mRNA KHDRBS1 GDSC1000 AAC 0.24 4e-13
mRNA HDAC2 GDSC1000 AAC 0.24 7e-13
Download CSV