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UNC0638

Synonyms

SourcesNames Used
GDSC1000, CTRPv2UNC0638
PharmacoGx UNC0638

External IDs

DatabaseIdentifier
Smiles: CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)C5CCCCC5
Inchikey: QOECJCJVIMVJGX-UHFFFAOYSA-N
Pubchem: 46224516

Annotated Targets

EHMT1, EHMT2

Cell lines tested with UNC0638

1316 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung GDSC1000, CTRPv24
CCF-STTG1 central nervous system GDSC1000, CTRPv24
A375 skin GDSC1000, CTRPv24
CAL-51 breast GDSC1000, CTRPv24
NCI-H460 lung GDSC1000, CTRPv24
LOXIMVI haematopoietic and lymphoid tissue GDSC1000, CTRPv24
NCI-H1869 lung GDSC1000, CTRPv24
AsPC-1 pancreas GDSC1000, CTRPv24
OAW-28 ovary GDSC1000, CTRPv24
DU-145 prostate GDSC1000, CTRPv24
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Top molecular features associated with response to UNC0638


Feature TypeStandardized
Nominal ANOVA
mRNA ATP6V1B2 GDSC1000 AAC 0.21 2e-10
mRNA ZFP36 GDSC1000 AAC -0.21 4e-10
mRNA PLBD1 GDSC1000 AAC -0.22 7e-10
mRNA N4BP2 CTRPv2 AAC 0.24 3e-09
mRNA DTNA GDSC1000 AAC 0.18 4e-09
mRNA DNMT3A CTRPv2 AAC 0.23 4e-09
mRNA CYR61 GDSC1000 AAC -0.24 6e-09
mRNA CECR6 GDSC1000 AAC 0.17 1e-08
mRNA DCX GDSC1000 AAC 0.18 2e-08
mRNA HEATR5A GDSC1000 AAC -0.18 2e-08
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