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thapsigargin

Synonyms

SourcesNames Used
GDSC1000Thapsigargin
gCSIthapsigargin
PharmacoGx thapsigargin

External IDs

DatabaseIdentifier
Smiles: CCCCCCCC(=O)O[C@@H]1[C@@H](OC(=O)/C(=CC)/C)C(=C2[C@@H]3OC(=O)[C@@](C)(O)[C@@]3(O)[C@H](C[C@](C)(OC(=O)C)[C@@H]12)OC(=O)CCC)C
Inchikey: IXFPJGBNCFXKPI-FSIHEZPISA-N
Pubchem: 446378

Cell lines tested with thapsigargin

994 cell lines have been tested with this compound, using data from 2 dataset(s).
G-402 soft tissue GDSC1000, gCSI2
Calu-3 lung GDSC1000, gCSI2
Mewo skin GDSC1000, gCSI2
NCI-H2009 lung GDSC1000, gCSI2
AsPC-1 pancreas GDSC1000, gCSI2
ChaGo-K-1 lung GDSC1000, gCSI2
SNU-475 liver GDSC1000, gCSI2
NCI-H2170 lung GDSC1000, gCSI2
SW1463 large intestine GDSC1000, gCSI2
ACHN kidney GDSC1000, gCSI2
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Top molecular features associated with response to thapsigargin


Feature TypeStandardized
Nominal ANOVA
mRNA NOB1 GDSC1000 AAC 0.26 7e-13
mRNA WDR74 GDSC1000 AAC 0.26 7e-13
mRNA DDX21 GDSC1000 AAC 0.25 9e-12
mRNA ADGRG1 gCSI AAC -0.44 2e-10
mRNA CLPX GDSC1000 AAC 0.23 4e-10
mRNA C10orf2 GDSC1000 AAC 0.23 1e-09
mRNA LYAR GDSC1000 AAC 0.22 1e-09
mRNA HDAC11 gCSI AAC -0.39 3e-09
mRNA ASCL1 GDSC1000 AAC -0.23 4e-09
mRNA NPM3 GDSC1000 AAC 0.2 5e-09
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