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staurosporine

Synonyms

SourcesNames Used
CTRPv2staurosporine
PharmacoGx staurosporine

External IDs

DatabaseIdentifier
Smiles: CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35
Inchikey: HKSZLNNOFSGOKW-FYTWVXJKSA-N
Pubchem: 44259

Annotated Targets

LCK, PIM1, ITK, SYK, MAPKAPK2, GSK3B, CSK, CDK2, PIK3CG, PDPK1, PRKCQ, ZAP70

Cell lines tested with staurosporine

219 cell lines have been tested with this compound, using data from 1 dataset(s).
NCI-H1299 lung CTRPv22
SUIT-2 pancreas CTRPv22
YD-38 upper aerodigestive tract CTRPv21
YD-15 salivary gland CTRPv21
YD-10B upper aerodigestive tract CTRPv21
TE-9 oesophagus CTRPv21
TE-10 oesophagus CTRPv21
SNU-899 upper aerodigestive tract CTRPv21
SNU-668 stomach CTRPv21
SNU-5 stomach CTRPv21
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Top molecular features associated with response to staurosporine


Feature TypeStandardized
Nominal ANOVA
mRNA ITGAL CTRPv2 AAC 0.49 1e-10
mRNA CCDC182 CTRPv2 AAC 0.44 2e-10
mRNA FLT3 CTRPv2 AAC 0.42 5e-10
mRNA LAMP5 CTRPv2 AAC 0.43 5e-10
mRNA CXorf21 CTRPv2 AAC 0.44 6e-10
mRNA KCNN2 CTRPv2 AAC 0.42 9e-10
mRNA PPP1R27 CTRPv2 AAC 0.4 1e-09
mRNA CCR2 CTRPv2 AAC 0.4 3e-09
mRNA MYBPH CTRPv2 AAC 0.39 5e-09
mRNA AC114783.1 CTRPv2 AAC 0.43 1e-08
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