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barasertib

Synonyms

SourcesNames Used
CTRPv2barasertib
PharmacoGx barasertib

External IDs

DatabaseIdentifier
Smiles: CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)ncnc2c1
Pubchem: 11497983

Annotated Targets

AURKA, AURKB

Cell lines tested with barasertib

826 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to barasertib


Feature TypeStandardized
Nominal ANOVA
mRNA BAHCC1 CTRPv2 AAC 0.31 3e-23
mRNA CBX2 CTRPv2 AAC 0.35 5e-23
mRNA CDCA7 CTRPv2 AAC 0.34 2e-22
mRNA MBTD1 CTRPv2 AAC 0.36 4e-21
mRNA ZBED4 CTRPv2 AAC 0.34 5e-20
mRNA CASP2 CTRPv2 AAC 0.32 6e-20
mRNA FAM117B CTRPv2 AAC 0.3 1e-19
mRNA ZNF184 CTRPv2 AAC 0.32 8e-19
mRNA FBRSL1 CTRPv2 AAC 0.29 1e-18
mRNA YPEL1 CTRPv2 AAC 0.29 9e-18
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