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PHA-665752

Synonyms

SourcesNames Used
CCLE, GDSC1000PHA-665752
PharmacoGx PHA-665752

External IDs

DatabaseIdentifier
Smiles: CC1=C(NC(=C1C(=O)N2CCCC2CN3CCCC3)C)C=C4C5=C(C=CC(=C5)S(=O)(=O)CC6=C(C=CC=C6Cl)Cl)NC4=O
Inchikey: OYONTEXKYJZFHA-SSHUPFPWSA-N
Pubchem: 10461815

Annotated Targets

MET

Cell lines tested with PHA-665752

823 cell lines have been tested with this compound, using data from 2 dataset(s).
UACC-812 breast CCLE, GDSC10002
UACC-257 haematopoietic and lymphoid tissue CCLE, GDSC10002
U-87-MG central nervous system CCLE, GDSC10002
Toledo haematopoietic and lymphoid tissue CCLE, GDSC10002
TE-9 oesophagus CCLE, GDSC10002
TE-5 oesophagus CCLE, GDSC10002
TE-15 oesophagus CCLE, GDSC10002
TE-11 oesophagus CCLE, GDSC10002
TE-1 oesophagus CCLE, GDSC10002
TC-71 bone CCLE, GDSC10002
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Top molecular features associated with response to PHA-665752


Feature TypeStandardized
Nominal ANOVA
mRNA SLC15A1 GDSC1000 AAC 0.34 9e-12
mRNA NMUR2 GDSC1000 AAC 0.33 2e-09
mRNA NR5A2 GDSC1000 AAC 0.3 7e-09
mRNA CYP2W1 GDSC1000 AAC 0.28 6e-08
mRNA XAF1 CCLE AAC 0.24 4e-07
mRNA NPSR1 GDSC1000 AAC 0.24 2e-06
mRNA SCARA5 GDSC1000 AAC 0.24 2e-06
mRNA KLHDC7B CCLE AAC 0.22 2e-06
mRNA NKG7 CCLE AAC 0.24 3e-06
mRNA FGFRL1 GDSC1000 AAC 0.27 3e-06
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