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PF-543

Synonyms

SourcesNames Used
CTRPv2PF-543
PharmacoGx PF-543

External IDs

DatabaseIdentifier
Smiles: Cc1cc(CS(=O)(=O)c2ccccc2)cc(OCc2ccc(CN3CCC[C@@H]3CO)cc2)c1
Pubchem: 66577038

Annotated Targets

SPHK1

Cell lines tested with PF-543

829 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Top molecular features associated with response to PF-543


Feature TypeStandardized
Nominal ANOVA
mRNA C17orf98 CTRPv2 AAC 0.23 1e-10
mRNA KRTAP13-2 CTRPv2 AAC 0.24 1e-10
mRNA TEX13B CTRPv2 AAC 0.18 6e-07
mRNA FAM9A CTRPv2 AAC 0.17 2e-06
mRNA HTR2B CTRPv2 AAC 0.17 3e-06
mRNA PAGE3 CTRPv2 AAC 0.17 4e-06
mRNA VCX2 CTRPv2 AAC 0.17 5e-06
mRNA CCDC172 CTRPv2 AAC 0.16 7e-06
mRNA VCX3A CTRPv2 AAC 0.16 1e-05
mRNA TFE3 CTRPv2 AAC -0.18 1e-05
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