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AZD1480

Synonyms

SourcesNames Used
CTRPv2AZD1480
PharmacoGx AZD1480

External IDs

DatabaseIdentifier
Smiles: CC(Nc1ncc(Cl)c(Nc2cc(C)[nH]n2)n1)c1ncc(F)cn1
Pubchem: 16659841

Annotated Targets

JAK2, JAK1, JAK3

Cell lines tested with AZD1480

419 cell lines have been tested with this compound, using data from 1 dataset(s).
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
YAMATO N/A CTRPv21
TTC709 N/A CTRPv21
TM87-16 N/A CTRPv21
SYO1 N/A CTRPv21
SW982 soft tissue CTRPv21
BT16 N/A CTRPv21
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Top molecular features associated with response to AZD1480


Feature TypeStandardized
Nominal ANOVA
mRNA OSM CTRPv2 AAC 0.45 8e-19
mRNA CISH CTRPv2 AAC 0.45 2e-18
mRNA CD3D CTRPv2 AAC 0.4 3e-16
mRNA GBP5 CTRPv2 AAC 0.41 6e-16
mRNA GIMAP1 CTRPv2 AAC 0.4 7e-16
mRNA ITK CTRPv2 AAC 0.4 7e-16
mRNA CD7 CTRPv2 AAC 0.4 8e-16
mRNA GIMAP7 CTRPv2 AAC 0.39 1e-15
mRNA CD3E CTRPv2 AAC 0.39 1e-15
mRNA RGPD3 CTRPv2 AAC 0.4 1e-15
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