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SourcesNames Used
GDSC1000, CTRPv2OSI-930
PharmacoGx OSI-930

External IDs

Smiles: FC(F)(F)Oc1ccc(NC(=O)c2sccc2NCc2ccnc3ccccc23)cc1
Pubchem: 9868037

Annotated Targets


Cell lines tested with OSI-930

1232 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung CTRPv23
CCF-STTG1 central nervous system GDSC1000, CTRPv23
CAL-51 breast GDSC1000, CTRPv23
OAW-28 ovary GDSC1000, CTRPv23
NCI-H1869 lung GDSC1000, CTRPv23
NCI-H460 lung GDSC1000, CTRPv23
NCI-H1299 lung GDSC1000, CTRPv23
DU-145 prostate GDSC1000, CTRPv23
A375 skin GDSC1000, CTRPv23
AsPC-1 pancreas GDSC1000, CTRPv23
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Top molecular features associated with response to OSI-930

Feature TypeStandardized
Nominal ANOVA
mRNA CSF1R GDSC1000 AAC 0.37 2e-26
mRNA TRH GDSC1000 AAC 0.31 7e-22
mRNA VSIG4 GDSC1000 AAC 0.32 8e-22
mRNA PLPPR3 GDSC1000 AAC 0.26 7e-14
mRNA PRAM1 GDSC1000 AAC 0.26 2e-13
mRNA PRTN3 GDSC1000 AAC 0.24 6e-13
mRNA CD300LF GDSC1000 AAC 0.26 7e-13
mRNA LST1 GDSC1000 AAC 0.29 2e-12
mRNA PRSS57 GDSC1000 AAC 0.26 2e-12
mRNA CD34 GDSC1000 AAC 0.23 5e-12
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