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OSI-906

Synonyms

SourcesNames Used
CTRPv2linsitinib
PharmacoGx OSI-906

External IDs

DatabaseIdentifier
Smiles: CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O
Inchikey: PKCDDUHJAFVJJB-UHFFFAOYSA-N
Pubchem: 11640390

Cell lines tested with OSI-906

835 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to OSI-906


Feature TypeStandardized
Nominal ANOVA
mRNA RP4-583P15.14 CTRPv2 AAC 0.44 1e-38
mRNA LIME1 CTRPv2 AAC 0.43 4e-36
mRNA RP4-583P15.15 CTRPv2 AAC 0.39 4e-30
mRNA GOLGA8S CTRPv2 AAC 0.37 2e-27
mRNA TNFRSF17 CTRPv2 AAC 0.37 1e-26
mRNA PRDM1 CTRPv2 AAC 0.37 3e-25
mRNA ZBP1 CTRPv2 AAC 0.35 6e-25
mRNA GPRC5D CTRPv2 AAC 0.33 1e-22
mRNA TXNDC5 CTRPv2 AAC 0.33 4e-22
mRNA RNF122 CTRPv2 AAC 0.34 6e-22
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