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AT-7519

Synonyms

SourcesNames Used
GDSC1000AT-7519
PharmacoGx AT-7519

External IDs

DatabaseIdentifier
Smiles: Clc1cccc(Cl)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCNCC1
Pubchem: 11338033

Annotated Targets

CDK14, CDK1, CDK2, CDK4, CDK5, CDK6, CDK9

Cell lines tested with AT-7519

984 cell lines have been tested with this compound, using data from 1 dataset(s).
YMB-1-E breast GDSC10001
SUP-T1 haematopoietic and lymphoid tissue GDSC10001
NEC8 testis GDSC10001
RT-112 urinary tract GDSC10001
NCI-H1755 lung GDSC10001
NCI-H1836 lung GDSC10001
D-283MED central nervous system GDSC10001
RCM-1 large intestine GDSC10001
SK-MG-1 central nervous system GDSC10001
ROS-50 haematopoietic and lymphoid tissue GDSC10001
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Top molecular features associated with response to AT-7519


Feature TypeStandardized
Nominal ANOVA
mRNA ABCB1 GDSC1000 AAC -0.29 6e-19
mRNA PRPF4B GDSC1000 AAC 0.22 7e-13
mRNA CCAR1 GDSC1000 AAC 0.22 2e-11
mRNA ZNF232 GDSC1000 AAC 0.19 5e-11
mRNA DUSP3 GDSC1000 AAC -0.21 1e-10
mRNA MDFI GDSC1000 AAC 0.2 2e-10
mRNA CREB1 GDSC1000 AAC 0.2 3e-10
mRNA CTSA GDSC1000 AAC -0.21 6e-10
mRNA CD63 GDSC1000 AAC -0.22 1e-09
mRNA SNRNP48 GDSC1000 AAC 0.19 2e-09
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