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JQ-1

Synonyms

SourcesNames Used
GDSC1000JQ1
CTRPv2JQ-1
PharmacoGx JQ-1

External IDs

DatabaseIdentifier
Smiles: CC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)C(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C
Inchikey: DOXYOPGGFSMXOX-GOSISDBHSA-N
Pubchem: 71300862

Annotated Targets

BRDT

Cell lines tested with JQ-1

1319 cell lines have been tested with this compound, using data from 2 dataset(s).
A549 lung GDSC1000, CTRPv24
NCI-H1869 lung GDSC1000, CTRPv24
NCI-H460 lung GDSC1000, CTRPv24
NCI-H1299 lung GDSC1000, CTRPv24
CAL-51 breast GDSC1000, CTRPv24
OAW-28 ovary GDSC1000, CTRPv24
DU-145 prostate GDSC1000, CTRPv24
CCF-STTG1 central nervous system GDSC1000, CTRPv24
A375 skin GDSC1000, CTRPv24
AsPC-1 pancreas GDSC1000, CTRPv24
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Top molecular features associated with response to JQ-1


Feature TypeStandardized
Nominal ANOVA
mRNA MBTD1 CTRPv2 AAC 0.25 1e-11
mRNA MYOF CTRPv2 AAC -0.22 3e-09
mRNA KANSL1 CTRPv2 AAC 0.2 5e-09
mRNA RCOR3 CTRPv2 AAC 0.19 7e-09
mRNA ZBED4 CTRPv2 AAC 0.21 1e-08
mRNA MANBAL CTRPv2 AAC -0.22 4e-08
mRNA HCCS CTRPv2 AAC -0.17 5e-08
mRNA RMND5A CTRPv2 AAC 0.19 7e-08
mRNA SLC35E2B CTRPv2 AAC 0.17 1e-07
mRNA DCAF7 CTRPv2 AAC 0.19 2e-07
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