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SourcesNames Used
PharmacoGx AS605240

External IDs

Smiles: O=C1NC(=O)C(S1)=C/c1ccc2nccnc2c1
Pubchem: 5289247

Cell lines tested with AS605240

984 cell lines have been tested with this compound, using data from 1 dataset(s).
NCI-H292 lung GDSC10001
SK-CO-1 large intestine GDSC10001
DMS-79 lung GDSC10001
OCI-AML3 haematopoietic and lymphoid tissue GDSC10001
D-336MG central nervous system GDSC10001
ST486 haematopoietic and lymphoid tissue GDSC10001
CAL-27 upper aerodigestive tract GDSC10001
OE33 oesophagus GDSC10001
OMC-1 cervix GDSC10001
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Top molecular features associated with response to AS605240

Feature TypeStandardized
Nominal ANOVA
mRNA CTSG GDSC1000 AAC 0.23 7e-11
mRNA SPRY2 GDSC1000 AAC 0.24 7e-11
mRNA SPRY1 GDSC1000 AAC 0.21 1e-09
mRNA DUSP6 GDSC1000 AAC 0.21 1e-09
mRNA TBC1D8 GDSC1000 AAC 0.22 2e-09
mRNA LCP2 GDSC1000 AAC 0.27 3e-09
mRNA LAIR1 GDSC1000 AAC 0.26 3e-09
mRNA PPP1R27 GDSC1000 AAC 0.19 4e-09
mRNA AIF1 GDSC1000 AAC 0.23 6e-09
mRNA PTPRE GDSC1000 AAC 0.2 1e-08
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