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SourcesNames Used
PharmacoGx AS601245

External IDs

Smiles: C1=CC=C2C(=C1)NC(=C(C#N)C3=NC(=NC=C3)NCCC4=CN=CC=C4)S2
Pubchem: 11422035

Cell lines tested with AS601245

932 cell lines have been tested with this compound, using data from 1 dataset(s).
UMC-11 lung GDSC10001
HCC1143 breast GDSC10001
K2 thyroid GDSC10001
MDA-MB-436 breast GDSC10001
NB1 autonomic ganglia GDSC10001
DEL haematopoietic and lymphoid tissue GDSC10001
JEG-3 placenta GDSC10001
MKN1 stomach GDSC10001
MDA-MB-453 breast GDSC10001
MDA-MB-361 breast GDSC10001
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Top molecular features associated with response to AS601245

Feature TypeStandardized
Nominal ANOVA
mRNA PCSK2 GDSC1000 AAC -0.22 2e-09
mRNA SV2B GDSC1000 AAC -0.2 5e-08
mRNA ZMAT4 GDSC1000 AAC -0.2 8e-08
mRNA TNFRSF12A GDSC1000 AAC 0.26 1e-07
mRNA CCP110 GDSC1000 AAC -0.19 2e-07
mRNA GDAP1 GDSC1000 AAC -0.19 2e-07
mRNA NCAM1 GDSC1000 AAC -0.2 2e-07
mRNA INSM1 GDSC1000 AAC -0.19 2e-07
mRNA TIGD3 GDSC1000 AAC -0.19 3e-07
mRNA FAM184A GDSC1000 AAC -0.2 3e-07
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