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alisertib

Synonyms

SourcesNames Used
CTRPv2alisertib
PharmacoGx alisertib

External IDs

DatabaseIdentifier
Smiles: COc1cc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2OC)ccc1C(O)=O
Pubchem: 24771867

Annotated Targets

AURKA, AURKB

Cell lines tested with alisertib

838 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to alisertib


Feature TypeStandardized
Nominal ANOVA
mRNA TPM2 CTRPv2 AAC 2.9e-05 1
mRNA RLN3 CTRPv2 AAC -2.6e-05 1
mRNA FAM136A CTRPv2 AAC -2.9e-05 1
mRNA PTPRZ1 CTRPv2 AAC 2.7e-05 1
mRNA EXOC6B CTRPv2 AAC 2.9e-05 1
mRNA CT45A9 CTRPv2 AAC -2.1e-05 1
mRNA SLC25A27 CTRPv2 AAC 2e-05 1
mRNA IL2RA CTRPv2 AAC -1.9e-05 1
mRNA WHRN CTRPv2 AAC -1.7e-05 1
mRNA TEP1 CTRPv2 AAC 1.5e-05 1
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