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alisertib

Synonyms

SourcesNames Used
CTRPv2alisertib
PharmacoGx alisertib

External IDs

DatabaseIdentifier
Smiles: COc1cc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2OC)ccc1C(O)=O
Pubchem: 24771867

Annotated Targets

AURKA, AURKB

Cell lines tested with alisertib

838 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
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Top molecular features associated with response to alisertib


Feature TypeStandardized
Nominal ANOVA
mRNA A1BG CTRPv2 AAC -0.012 0.7
mRNA A1CF CTRPv2 AAC -0.019 0.6
mRNA A2M CTRPv2 AAC -0.021 0.5
mRNA A2ML1 CTRPv2 AAC 0.0065 0.8
mRNA A3GALT2 CTRPv2 AAC -0.03 0.3
mRNA A4GALT CTRPv2 AAC -0.087 0.008
mRNA A4GNT CTRPv2 AAC -0.029 0.3
mRNA AAAS CTRPv2 AAC 0.072 0.03
mRNA AACS CTRPv2 AAC -0.01 0.8
mRNA AADAC CTRPv2 AAC 0.014 0.7
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