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SourcesNames Used
PharmacoGx AGK-2

External IDs

Smiles: C1=CC2=C(C=CC=N2)C(=C1)NC(=O)C(=CC3=CC=C(O3)C4=C(C=CC(=C4)Cl)Cl)C#N
Pubchem: 2130404

Annotated Targets


Cell lines tested with AGK-2

829 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
AsPC-1 pancreas CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Top molecular features associated with response to AGK-2

Feature TypeStandardized
Nominal ANOVA
mRNA FDCSP CTRPv2 AAC 0.31 1e-18
mRNA ENPP6 CTRPv2 AAC 0.29 1e-15
mRNA CSN3 CTRPv2 AAC 0.28 2e-15
mRNA GDPD4 CTRPv2 AAC 0.25 1e-11
mRNA GABRP CTRPv2 AAC 0.23 2e-10
mRNA STARD3 CTRPv2 AAC 0.24 2e-10
mRNA KLRF2 CTRPv2 AAC 0.23 2e-10
mRNA EDNRB CTRPv2 AAC 0.24 6e-10
mRNA GRM3 CTRPv2 AAC 0.23 6e-10
mRNA ADAD2 CTRPv2 AAC 0.21 2e-08
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