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SourcesNames Used
PharmacoGx AG-014699

External IDs

Smiles: CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=CC(=CC(=C34)N2)F.OP(=O)(O)O
Pubchem: 9931953

Cell lines tested with AG-014699

965 cell lines have been tested with this compound, using data from 1 dataset(s).
SK-LMS-1 soft tissue GDSC10001
RH-41 soft tissue GDSC10001
M059J central nervous system GDSC10001
MCC26 skin GDSC10001
HCC1806 breast GDSC10001
SK-MEL-24 skin GDSC10001
LP-1 haematopoietic and lymphoid tissue GDSC10001
Geo large intestine GDSC10001
GI-1 central nervous system GDSC10001
SAS upper aerodigestive tract GDSC10001
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Top molecular features associated with response to AG-014699

Feature TypeStandardized
Nominal ANOVA
mRNA MFSD2B GDSC1000 AAC -0.17 7e-07
mRNA CHD3 GDSC1000 AAC 0.17 1e-06
mRNA LGI4 GDSC1000 AAC 0.16 2e-06
mRNA C1orf54 GDSC1000 AAC 0.18 2e-06
mRNA C1QA GDSC1000 AAC -0.15 7e-06
mRNA NHSL2 GDSC1000 AAC -0.15 1e-05
mRNA MERTK GDSC1000 AAC 0.15 1e-05
mRNA TCF7L2 GDSC1000 AAC 0.17 1e-05
mRNA SIGLEC8 GDSC1000 AAC -0.15 1e-05
mRNA TXNDC2 GDSC1000 AAC -0.14 1e-05
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