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ABT-737

Synonyms

SourcesNames Used
CTRPv2ABT-737
PharmacoGx ABT-737

External IDs

DatabaseIdentifier
Smiles: CN(C)CCC(CSC1=CC=CC=C1)NC2=C(C=C(C=C2)S(=O)(=O)NC(=O)C3=CC=C(C=C3)N4CCN(CC4)CC5=CC=CC=C5C6=CC=C(C=C6)Cl)[N+](=O)[O-]
Inchikey: HPLNQCPCUACXLM-PGUFJCEWSA-N
Pubchem: 11228183

Annotated Targets

BCL2, BCL2L1, BCL2L2

Cell lines tested with ABT-737

773 cell lines have been tested with this compound, using data from 1 dataset(s).
A549 lung CTRPv23
DU-145 prostate CTRPv22
NCI-H1869 lung CTRPv22
CCF-STTG1 central nervous system CTRPv22
OAW-28 ovary CTRPv22
HeLa cervix CTRPv22
LOXIMVI haematopoietic and lymphoid tissue CTRPv22
NCI-H520 lung CTRPv22
MKN74 stomach CTRPv22
IGROV-1 ovary CTRPv22
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Top molecular features associated with response to ABT-737


Feature TypeStandardized
Nominal ANOVA
mRNA NEURL1B CTRPv2 AAC 0.32 3e-18
mRNA ARHGAP33 CTRPv2 AAC 0.32 3e-17
mRNA BCL2 CTRPv2 AAC 0.32 6e-16
mRNA ACTL6B CTRPv2 AAC 0.3 2e-15
mRNA KIAA1147 CTRPv2 AAC 0.28 2e-14
mRNA FIZ1 CTRPv2 AAC 0.28 2e-14
mRNA CELF4 CTRPv2 AAC 0.28 3e-14
mRNA ZNF737 CTRPv2 AAC 0.28 5e-14
mRNA ZNF606 CTRPv2 AAC 0.28 7e-14
mRNA VPS4B CTRPv2 AAC 0.26 8e-14
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